Crosslinking, Labeling and Protein Modification
Broadpharm Bromo-PEG3-CH2CO2tBu | 2100306-71-4 | MFCD30723231 | 500mg
Bromo-PEG3-CH2CO2tBu | Putity: 98% | MW: 327.2 | 2100306-71-4 | MFCD30723231 | 500mg
Medchemexpress LLC Propargyl-PEG4-CH2COOH | 1429934-37-1 | >97.0% | 290.31 | 25 MG
Propargyl-PEG4-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. It acts as a click chemistry reagent, featuring an Alkyne group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Azide-containing molecules. PROTACs, composed of two ligands linked together, target an E3 ubiquitin ligase and a specific protein, thereby utilizing the intracellular ubiquitin-proteasome system for selective protein degradation.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Click chemistry reagent
- Features Alkyne group for CuAAc
- Enables selective protein degradation via ubiquitin-proteasome system
Medchemexpress LLC endo-BCN-PEG2-alcohol | 1807501-85-4 | 98.0% | 325.40 | 25 MG
endo-BCN-PEG2-alcohol is a PEG-based PROTAC linker employed in the synthesis of PROTACs. This compound functions as a click chemistry reagent, featuring a BCN group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
- PEG-based PROTAC linker.
- Used in the synthesis of PROTACs.
- Functions as a click chemistry reagent.
- Contains a BCN group for strain-promoted alkyne-azide cycloaddition (SPAAC).
Medchemexpress LLC 2,5,8,11-Tetraoxatridecane, 13-azido- | 606130-90-9 | 98.0% | C9H19N3O4 | 50 MG
2,5,8,11-Tetraoxatridecane, 13-azido- is a chemical compound with a molecular weight of 233.26. It appears as a colorless to light yellow liquid and is intended for research use only. This product has been tested and complies with the given specifications.
- Colorless to light yellow liquid appearance
- Molecular weight of 233.26
- Suitable for research applications
- Storage in pure form at -20°C for 3 years
- Storage in solvent at -80°C for 6 months
- Storage in solvent at -20°C for 1 month
Medchemexpress LLC Biotin-PEG1-NH2 | 811442-85-0 | >98.0% | 330.45 g/mol | C14H26N4O3S | 50 MG
Biotin-PEG1-NH2 is a single-unit polyethylene glycol (PEG1) linker bearing a biotin tag and a terminal primary amine. It is used as a cleavable ADC linker or bioconjugation handle to introduce biotin for detection, purification, or targeting in antibody-drug conjugates and other conjugation workflows.
- Cleavable one-unit PEG linker for ADC synthesis.
- Biotin tag enables affinity capture and detection.
- Terminal amine for coupling to activated esters or crosslinkers.
- High purity suitable for research applications.
- Powder form; store under low-temperature, dry conditions.
Medchemexpress LLC DOTA-PEG5-amine | 98.0% | 666.76 | 50 MG
DOTA-PEG5-amine is a PEG-based PROTAC linker designed for the synthesis of PROTACs. These molecules feature two ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other a target protein. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade specific target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Medchemexpress LLC Dspe-peg-biotin | 385437-57-0 | 99.93% | 100 MG
DSPE-PEG-Biotin, MW 2000 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Peg-based PROTAC linker.
- Used in the synthesis of PROTACs.
- Can be dissolved in DMSO and H2O for in vitro experiments.
- Multiple dissolution protocols are available for in vivo experiments using various co-solvents like DMSO, PEG300, Tween-80, Saline, SBE-β-CD, and Corn Oil.
Medchemexpress LLC Methyltetrazine-PEG5-alkyne | 1802907-97-6 | 98.0% | C20H26N4O5 | 250 MG
Methyltetrazine-PEG5-alkyne is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It is provided as a pink to red solid with a purity of 98.0% for research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Purity of 98.0%
- Appearance: pink to red solid
- Store at 4°C, under nitrogen
- Soluble in DMSO
Medchemexpress LLC Mal-PEG4-VC-PAB-DMEA-PNU-159682 | 2259318-52-8 | 96.2% | 1559.62 | C74H98N10O27 | 1 MG
Mal-PEG4-VC-PAB-DMEA-PNU-159682 is a drug-linker conjugate used in antibody-drug conjugate (ADC) research. It combines a cleavable maleimide-PEG4-valine-citrulline-PAB-DMEA linker with a potent cytotoxic payload to enable studies of conjugation chemistry, linker stability, and payload release in vitro.
- Cleavable valine-citrulline peptide linker enabling enzymatic release.
- Maleimide functional group for thiol conjugation to antibodies.
- PEG4 spacer to improve solubility and spacing between antibody and payload.
- Conjugated to a potent cytotoxin for payload delivery studies.
- Supplied in small pack sizes suitable for early stage research.
Worthington Biochemical Corporation STEMXYME 1 COLLAGENAS 5X50MG
A specialized combination of Animal Origin-Free Clostridium histolyticum collagenase (Code: CLSAFB) and animal origin free Bacillus polymyxa neutral protease with a minimum of 250 CLS units and 1,000 caseinase units per mg dry weight. Designed for stem cell and other primary cell isolations and bioprocessing applications where introduction of potential animal derived pathogens must be prevented. 2593-92-3
Medchemexpress LLC Biotin-PEG2-acid | 1365655-89-5 | >97.0% | 403.49 g/mol | C17H29N3O6S | 50 MG
Biotin-PEG2-acid is a non-cleavable, two-unit polyethylene glycol (PEG) linker bearing a biotin affinity tag and a terminal carboxylic acid. It is supplied as an off-white to gray solid and is used to introduce hydrophilicity and a biotin handle in conjugation chemistries such as ADC and PROTAC synthesis.
- Non-cleavable two-unit PEG spacer improves solubility and linker flexibility.
- Terminal carboxylic acid enables standard conjugation chemistries.
- Biotin tag allows affinity capture and detection.
- High purity suitable for research applications.
- Available in multiple pack sizes including 50 MG for small-scale use.
Medchemexpress LLC Mal-PEG4-VA-PBD | 1342820-68-1 | 1294.40 g/mol | C68H79N9O17 | 1 MG
Mal-PEG4-VA-PBD is an agent-linker conjugate for antibody-drug conjugate (ADC) development that incorporates a pyrrolobenzodiazepine (PBD) cytotoxic warhead linked via a maleimide-PEG4-valine-alanine (Mal-PEG4-VA) cleavable linker. It is intended for bioconjugation to antibodies through thiol-reactive maleimide chemistry.
- Agent-linker conjugate for ADC development.
- Pyrrolobenzodiazepine (PBD) cytotoxic payload.
- Maleimide-PEG4-valine-alanine cleavable linker for thiol conjugation.
- Suitable for bioconjugation to antibodies and other thiol-containing biomolecules.
- Supplied in milligram quantities for research use.
Revvity Health Sciences Inc PhenoVue Cell Painting Kit 10 x 384-wells
PhenoVue Cell Painting Kit 10 x 384-wells